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1

Analysis of acetylcholinesterase inhibitors: bioanalysis, degradation and metabolism

Lygia Azevedo Marques, Martin Giera, Henk Lingeman, Wilfried MA Niessen

Journal:

Biomedical Chromatography

Year:

2011

Language:

english

File:

PDF, 1.81 MB

english, 2011

2

Butyrate reduces appetite and activates brown adipose tissue via the gut-brain neural circuit

Li, Zhuang, Yi, Chun-Xia, Katiraei, Saeed, Kooijman, Sander, Zhou, Enchen, Chung, Chih Kit, Gao, Yuanqing, van den Heuvel, José K., Meijer, Onno C., Berbée, Jimmy F.P., Heijink, Marieke, Giera, Martin

Journal:

Year:

2017

Language:

english

File:

PDF, 9.70 MB

english, 2017

3

Multiresidue analytical method using dispersive solid-phase extraction and gas chromatography/ion trap mass spectrometry to determine pharmaceuticals in whole blood

Florian Plössl, Martin Giera, Franz Bracher

Journal:

Journal of Chromatography A

Year:

2006

Language:

english

File:

PDF, 253 KB

english, 2006

4

Recent Advancements in the LC- and GC-Based Analysis of Malondialdehyde (MDA): A Brief Overview

Martin Giera, Henk Lingeman, Wilfried M. A. Niessen

Journal:

Chromatographia

Year:

2012

Language:

english

File:

PDF, 242 KB

english, 2012

5

Lipid and lipid mediator profiling of human synovial fluid in rheumatoid arthritis patients by means of LC–MS/MS

Martin Giera, Andreea Ioan-Facsinay, Rene Toes, Fei Gao, Jesmond Dalli, André M. Deelder, Charles N. Serhan, Oleg A. Mayboroda

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2012

Language:

english

File:

PDF, 646 KB

english, 2012

6

Mild and selective labeling of malondialdehyde with 2-aminoacridone: assessment of urinary malondialdehyde levels

Giera, Martin, Kloos, Dick-Paul, Raaphorst, Alex, Mayboroda, Oleg A., Deelder, André M., Lingeman, Henk, Niessen, Wilfried M A.

Journal:

The Analyst (Royal Society of Chemistry)

Year:

2011

Language:

english

File:

PDF, 296 KB

english, 2011

7

Bioanalytical derivatization: is there still room for development?

Journal:

Year:

2015

File:

PDF, 934 KB

2015

8

Natural killer cells play an essential role in resolution of antigen-induced inflammation in mice

Anuforo, Osk U.U., Bjarnarson, Stefania P., Jonasdottir, Hulda S., Giera, Martin, Hardardottir, Ingibjorg, Freysdottir, Jona

Journal:

Molecular Immunology

Year:

2018

Language:

english

File:

PDF, 933 KB

english, 2018

9

[Methods in Molecular Biology] Clinical Metabolomics Volume 1730 || Metabolomics in Immunology Research

Year:

2018

Language:

english

File:

PDF, 209 KB

english, 2018

10

[Methods in Molecular Biology] Clinical Metabolomics Volume 1730 || Sphingolipid Analysis in Clinical Research

Year:

2018

Language:

english

File:

PDF, 286 KB

english, 2018

11

[Methods in Molecular Biology] Clinical Metabolomics Volume 1730 || Exploratory GC/MS-Based Metabolomics of Body Fluids

Year:

2018

Language:

english

File:

PDF, 135 KB

english, 2018

12

[Methods in Molecular Biology] Clinical Metabolomics Volume 1730 ||

Year:

2018

Language:

english

File:

PDF, 7.12 MB

english, 2018

13

[Methods in Molecular Biology] Clinical Metabolomics Volume 1730 || GC-MS Analysis of Lipid Oxidation Products in Blood, Urine, and Tissue Samples

Year:

2018

Language:

english

File:

PDF, 233 KB

english, 2018

14

KIMBLE: A versatile visual NMR metabolomics workbench in KNIME

Verhoeven, Aswin, Giera, Martin, Mayboroda, Oleg A.

Journal:

Analytica Chimica Acta

Year:

2018

Language:

english

File:

PDF, 3.55 MB

english, 2018

15

A gas chromatography–mass spectrometry-based whole-cell screening assay for target identification in distal cholesterol biosynthesis

Müller, Christoph, Junker, Julia, Bracher, Franz, Giera, Martin

Journal:

Nature Protocols

Year:

2019

Language:

english

File:

PDF, 1011 KB

english, 2019

16

Inhibition of Δ24-dehydrocholesterol reductase activates pro-resolving lipid mediator biosynthesis and inflammation resolution

Körner, Andreas, Zhou, Enchen, Müller, Christoph, Mohammed, Yassene, Herceg, Sandra, Bracher, Franz, Rensen, Patrick C. N., Wang, Yanan, Mirakaj, Valbona, Giera, Martin

Journal:

Proceedings of the National Academy of Sciences

Year:

2019

Language:

english

File:

PDF, 2.74 MB

english, 2019

17

Scientific workflow managers in metabolomics: an overview

Verhoeven, Aswin, Giera, Martin, Mayboroda, Oleg A.

Journal:

The Analyst (Royal Society of Chemistry)

Year:

2020

File:

PDF, 1.28 MB

2020

18

William Griffiths, Yuqin Wang (Eds.): Lipidomics: current and emerging techniques

Journal:

Analytical and Bioanalytical Chemistry

Year:

2020

File:

PDF, 313 KB

2020

19

High temperature liquid chromatography hyphenated with ESI-MS and ICP-MS detection for the structural characterization and quantification of halogen containing drug metabolites

Jon S.B. de Vlieger, Mark J.N. Giezen, David Falck, Cornelis Tump, Fred van Heuveln, Martin Giera, Jeroen Kool, Henk Lingeman, Jaap Wieling, Maarten Honing, Hubertus Irth, Wilfried M.A. Niessen

Journal:

Analytica Chimica Acta

Year:

2011

Language:

english

File:

PDF, 945 KB

english, 2011

20

Structural elucidation of biologically active neomycin N-octyl derivatives in a regioisomeric mixture by means of liquid chromatography/ion trap time-of-flight mass spectrometry

Martin Giera, Jon S. B. de Vlieger, Henk Lingeman, Hubertus Irth, Wilfried M. A. Niessen

Journal:

Rapid Communications in Mass Spectrometry

Year:

2010

Language:

english

File:

PDF, 237 KB

english, 2010

21

Development of an online p38α mitogen-activated protein kinase binding assay and integration of LC–HR-MS

David Falck, Jon S. B. de Vlieger, Wilfried M. A. Niessen, Jeroen Kool, Maarten Honing, Martin Giera, Hubertus Irth

Journal:

Analytical and Bioanalytical Chemistry

Year:

2010

Language:

english

File:

PDF, 878 KB

english, 2010

22

Development of a microfluidic confocal fluorescence detection system for the hyphenation of nano-LC to on-line biochemical assays

Ferry Heus, Martin Giera, Gerdien E. de Kloe, Dick van Iperen, Joost Buijs, Tariq T. Nahar, August B. Smit, Henk Lingeman, Iwan J. P. de Esch, Wilfried M. A. Niessen, Hubertus Irth, Jeroen Kool

Journal:

Analytical and Bioanalytical Chemistry

Year:

2010

Language:

english

File:

PDF, 468 KB

english, 2010

23

Advances in mass spectrometry-based post-column bioaffinity profiling of mixtures

Jeroen Kool, Martin Giera, Hubertus Irth, Wilfried M. A. Niessen

Journal:

Analytical and Bioanalytical Chemistry

Year:

2011

Language:

english

File:

PDF, 790 KB

english, 2011

24

Side chain azasteroids and thiasteroids as sterol methyltransferase inhibitors in ergosterol biosynthesis

Delphine Renard, Johann Perruchon, Martin Giera, Jörg Müller, Franz Bracher

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 470 KB

english, 2009

25

Photohuperzine A—A new photoisomer of huperzine A: Structure elucidation, formation kinetics and activity assessment

Lygia Azevedo Marques, Martin Giera, Frans J.J. de Kanter, Wilfried M.A. Niessen, Henk Lingeman, Hubertus Irth

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2010

Language:

english

File:

PDF, 362 KB

english, 2010

26

Stability-indicating study of the anti-Alzheimer's drug galantamine hydrobromide

Lygia Azevedo Marques, Ismail Maada, Frans J.J. de Kanter, Henk Lingeman, Hubertus Irth, Wilfried M.A. Niessen, Martin Giera

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2011

Language:

english

File:

PDF, 524 KB

english, 2011

27

Identification of the Biotransformation Products of 2-Ethylhexyl 4-(N,N-Dimethylamino)benzoate

Zacarias León, Jon de Vlieger, Alberto Chisvert, Amparo Salvador, Henk Lingeman, Hubertus Irth, Martin Giera

Journal:

Chromatographia

Year:

2010

Language:

english

File:

PDF, 411 KB

english, 2010

28

On-line electrochemistry–bioaffinity screening with parallel HR-LC-MS for the generation and characterization of modified p38α kinase inhibitors

David Falck, Jon S. B. de Vlieger, Martin Giera, Maarten Honing, Hubertus Irth, Wilfried M. A. Niessen, Jeroen Kool

Journal:

Analytical and Bioanalytical Chemistry

Year:

2012

Language:

english

File:

PDF, 616 KB

english, 2012

29

Inhibition of cholesterol biosynthesis disrupts lipid raft/caveolae and affects insulin receptor activation in 3T3-L1 preadipocytes

Jana Sánchez-Wandelmer, Alberto Dávalos, Emilio Herrera, Martin Giera, Sonia Cano, Gema de la Peña, Miguel A. Lasunción, Rebeca Busto

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2009

Language:

english

File:

PDF, 1010 KB

english, 2009

30

Haloperidol disrupts lipid rafts and impairs insulin signaling in SH-SY5Y cells

J. Sánchez-Wandelmer, A. Dávalos, G. de la Peña, S. Cano, M. Giera, A. Canfrán-Duque, F. Bracher, A. Martín-Hidalgo, C. Fernández-Hernando, M.A. Lasunción, R. Busto

Journal:

Year:

2010

Language:

english

File:

PDF, 1.14 MB

english, 2010

31

Fast and easy in vitro screening assay for cholesterol biosynthesis inhibitors in the post-squalene pathway

Martin Giera, Florian Plössl, Franz Bracher

Journal:

Year:

2007

Language:

english

File:

PDF, 350 KB

english, 2007

32

Lathosterol side chain amides—A new class of human lathosterol oxidase inhibitors

Martin Giera, Delphine Renard, Florian Plössl, Franz Bracher

Journal:

Year:

2008

Language:

english

File:

PDF, 437 KB

english, 2008

33

Erratum to: Recent Advancements in the LC- and GC-Based Analysis of Malondialdehyde (MDA): A Brief Overview

Giera, Martin, Lingeman, Henk, Niessen, Wilfried M. A.

Journal:

Chromatographia

Year:

2012

File:

PDF, 94 KB

2012

34

Protein Digestion: An Overview of the Available Techniques and Recent Developments

Switzar, Linda, Giera, Martin, Niessen, Wilfried M. A.

Journal:

Journal of Proteome Research

Year:

2013

Language:

english

File:

PDF, 372 KB

english, 2013

35

Evaluation of different column chemistries for fast urinary metabolic profiling

Kloos, Dick-Paul, Lingeman, Henk, Niessen, Wilfried M.A., Deelder, André M., Giera, Martin, Mayboroda, Oleg A.

Journal:

Journal of Chromatography B

Year:

2013

Language:

english

File:

PDF, 1.12 MB

english, 2013

36

On-Line Electrochemical Reduction of Disulfide Bonds: Improved FTICR-CID and -ETD Coverage of Oxytocin and Hepcidin

Nicolardi, Simone, Giera, Martin, Kooijman, Pieter, Kraj, Agnieszka, Chervet, Jean-Pierre, Deelder, André M., Burgt, Yuri E. M.

Journal:

Journal of the American Society for Mass Spectrometry

Year:

2013

Language:

english

File:

PDF, 643 KB

english, 2013

37

Comprehensive gas chromatography-electron ionisation mass spectrometric analysis of fatty acids and sterols using sequential one-pot silylation: quantification and isotopologue analysis

Kloos, Dick-Paul, Gay, Emmanuel, Lingeman, Henk, Bracher, Franz, Müller, Christoph, Mayboroda, Oleg A, Deelder, André M, Niessen, Wilfried M A, Giera, Martin

Journal:

Rapid Communications in Mass Spectrometry

Year:

2014

Language:

english

File:

PDF, 800 KB

english, 2014

38

Comparison of (bio-)transformation methods for the generation of metabolite-like compound libraries of p38α MAP kinase inhibitors using high-resolution screening

Falck, David, Rahimi Pirkolachachi, Fatie, Giera, Martin, Honing, Maarten, Kool, Jeroen, Niessen, Wilfried M.A.

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2014

Language:

english

File:

PDF, 586 KB

english, 2014

39

A convenient cellular assay for the identification of the molecular target of ergosterol biosynthesis inhibitors and quantification of their effects on total ergosterol biosynthesis

Müller, Christoph, Staudacher, Verena, Krauss, Jürgen, Giera, Martin, Bracher, Franz

Journal:

Year:

2013

Language:

english

File:

PDF, 907 KB

english, 2013

40

Microfractionation Revisited: A 1536 Well High Resolution Screening Assay

Giera, Martin, Heus, Ferry, Janssen, Laura, Kool, Jeroen, Lingeman, Henk, Irth, Hubertus

Journal:

Analytical Chemistry

Year:

2009

Language:

english

File:

PDF, 851 KB

english, 2009

41

Adipocyte-derived lipids modulate CD4 + T-cell function

Ioan-Facsinay, Andreea, Kwekkeboom, Joanneke C., Westhoff, Sanne, Giera, Martin, Rombouts, Yoann, van Harmelen, Vanessa, Huizinga, Tom W. J., Deelder, André, Kloppenburg, Margreet, Toes, René E. M.

Journal:

European Journal of Immunology

Year:

2013

Language:

english

File:

PDF, 730 KB

english, 2013

42

Analysis and Experimental Inhibition of Distal Cholesterol Biosynthesis

Giera, Martin, Müller, Christoph, Bracher, Franz

Journal:

Chromatographia

Year:

2015

Language:

english

File:

PDF, 808 KB

english, 2015

43

An Advanced LC–MS/MS Platform for the Analysis of Specialized Pro-Resolving Lipid Mediators

Jónasdóttir, Hulda S., Ioan-Facsinay, Andreea, Kwekkeboom, Joanneke, Brouwers, Hilde, Zuurmond, Anne-Marie, Toes, René, Deelder, André M., Giera, Martin

Journal:

Chromatographia

Year:

2015

Language:

english

File:

PDF, 1.27 MB

english, 2015

44

Protein costs do not explain evolution of metabolic strategies and regulation of ribosomal content: does protein investment explain an anaerobic bacterial Crabtree effect?

Goel, Anisha, Eckhardt, Thomas H., Puri, Pranav, de Jong, Anne, Branco dos Santos, Filipe, Giera, Martin, Fusetti, Fabrizia, de Vos, Willem M., Kok, Jan, Poolman, Bert, Molenaar, Douwe, Kuipers, Oscar

Journal:

Molecular Microbiology

Year:

2015

Language:

english

File:

PDF, 2.64 MB

english, 2015

45

Recent Developments in Clinical Omics

Giera, Martin, Wuhrer, Manfred

Journal:

Chromatographia

Year:

2015

Language:

english

File:

PDF, 213 KB

english, 2015

46

Differential Mobility Separation of Leukotrienes and Protectins

Jónasdóttir, Hulda S., Papan, Cyrus, Fabritz, Sebastian, Balas, Laurence, Durand, Thierry, Hardardottir, Ingibjorg, Freysdottir, Jona, Giera, Martin

Journal:

Analytical Chemistry

Year:

2015

Language:

english

File:

PDF, 877 KB

english, 2015

47

First Total Synthesis of Ergosta-5,8-dien-3β-ol

Journal:

Scientia Pharmaceutica

Year:

2008

Language:

english

File:

PDF, 222 KB

english, 2008

48

A hypomorphicCbx3allele causes prenatal growth restriction and perinatal energy homeostasis defects

Aydin, Ebru, Kloos, Dick-Paul, Gay, Emmanuel, Jonker, Willem, Hu, Lijuan, Bullwinkel, Jörn, Brown, Jeremy P, Manukyan, Maria, Giera, Martin, Singh, Prim B, Fundele, Reinald

Journal:

Journal of Biosciences

Year:

2015

Language:

english

File:

PDF, 3.84 MB

english, 2015

49

Fungal sterol C22-desaturase is not an antimycotic target as shown by selective inhibitors and testing on clinical isolates

Müller, Christoph, Binder, Ulrike, Maurer, Elisabeth, Grimm, Christian, Giera, Martin, Bracher, Franz

Journal:

Year:

2015

Language:

english

File:

PDF, 742 KB

english, 2015

50

Bioanalytical derivatization: is there still room for development?

Journal:

Year:

2015

Language:

english

File:

PDF, 934 KB

english, 2015